Understanding risk factors for the progression of essential tremor


  • Risk factors for the progression of essential tremor (ET) include female sex, a lack of family history of tremor, and presence of rest tremor at baseline. Cognitive and psychiatric comorbidities do not appear to be involved.

Why this matters?

  • ET is a common movement disorder associated with kinetic or upper limb lasting ≥3 years. Other motor features and cognitive and psychiatric disorders are common and may contribute to disease progression. This process is currently under investigated.

  • By identifying factors involved in the progression of ET, the paper may inform more tailored treatment and risk management, slowing or preventing the progression of ET and maintaining better of quality of life for patients.