Triptan medication for treatment of migraine attacks: is it a success or failure?


  • The European Headache Federation (EHF) defines both effective treatment for acute migraine and triptan failure in patients experiencing attacks.

Why this matters

  • Triptan use for acute therapy aims to reverse or stop the progression of a headache that has started. Previous studies present inconsistent findings on triptan use, hence a clear definition on triptan failure in clinical practice is necessary.

  • Standardized definitions may help inform decision-making on treatment and further support the design of future clinical trials to understand the complexities of migraine treatment.