Trait Conscientiousness predicts cognitive decline in people with multiple sclerosis


  • In people with multiple sclerosis (MS), higher baseline trait Conscientiousness predicts longitudinal cognitive decline as measured by the Symbol Digit Modalities Test (SDMT).

Why this matters

  • Predictors of longitudinal cognitive decline, such as more severe neuropathology or lower premorbid verbal intelligence, have previously been identified; personality, and in particular trait Conscientiousness, is another such candidate predictor.