TPP2 may play a broad inflammatory role in Multiple Sclerosis


  • A TPP2 mutation is causative for a case of familial, sterile brain inflammation mimicking non-progressive multiple sclerosis (MS), revealing a broader role for TPP2 in the inflammatory process of MS.

Why this matters

    The identification of missense mutations in TPP2 in patients with MS could better our understanding of the underlying causes of MS.