Takeaway
Children exposed to deprivation-related, but not threat-related, adverse experiences are more prone to faster cognitive decline later in life but this association is modified by social isolation.
Why this matters
Age-related morbidities such as cognitive decline, are a major public health concern. Previous studies have linked adverse childhood experiences (ACEs) with cognitive decline in memory, processing speed, and executive function in later life.
Understanding which ACEs may impact later cognition, and if social isolation is a modifiable risk factor, could allow amelioration of cognitive decline and allow clinicians to intervene during childhood or even later in life by promoting social integration.