Summary Summary Short summary of a recent publication, written by scientific experts. Published: 30 Jan 2023

The cholinergic basal forebrain as a structural biomarker for Parkinson’s disease

Cholinergic basal forebrain volume was found to be a reliable predictor of cholinergic nerve terminal loss. The strongest correlations were noted in the posterior cholinergic basal forebrain and temporofrontal, insula, cingulum, and hippocampal regions.
Therefore, the authors concluded that structural imaging of the cholinergic basal forebrain can be used as a reliable marker for regional cerebral vesicular acetylcholine transporter bindings, most notably in the anterior brain.