Temporal lobe epilepsy-related cortical thinning – does it run in the family?

Takeaway

  • Asymptomatic first-degree relatives (AFDRs) of people with mesial temporal lobe epilepsy (MTLE) induced by hippocampal sclerosis (HS) did not develop heritable cortical thinning.

Why this matters

  • Establishing heritability patterns of MTLE- and HS-related cortical thinning could aid early disease detection.