Technique for measuring spinal cord grey and white matter changes in motor neuron disease


  • Atrophy of spinal cord grey matter (GM) and white matter (WM) in patients with motor neuron disease (MND) can be reliably measured in a clinical setting using phase-sensitive inversion recovery (PSIR) imaging.

Why this matters

  • This novel imaging technique could benefit clinical management of motor neuron diseases by improving phenotypic characterization and assessment.