Smartphone-based symbol-digit modalities test can detect cognitive decline in multiple sclerosis


  • The symbol-digit modalities test is adaptable to Smartphone-based self-administered digital tests that accurately depict brain damage in multiple sclerosis.

Why this matters

    As multiple sclerosis progresses, reliable measurements of neurological disability are needed as an alternative to time-consuming neurological examination. The symbol-digit modalities test is a cognitive processing speed test traditionally administered by neuropsychologists. This novel study investigated the psychometric properties of digital Smartphone-based tests; the findings suggest that development of this novel technology could facilitate neurological care in multiple sclerosis by increasing accuracy while reducing cost.