Serological testing to identify trigger infections in patients with Guillain-Barré syndrome

Takeaway

  • Due to discrepancies between reported symptoms and serological results, along with the high rate of co-infections, broad serological testing is important to help identify the most likely infectious triggers in patients with Guillain-Barré syndrome (GBS).

Why this matters

  • The clinical features and disease severity of GBS varies across geographical regions, which may be due to differences in the distribution of preceding infections.

  • By studying differences in the distribution of preceding infections prior to GBS development, the clinical course and long-term prognosis of patients with GBS may be determined.