Restrictions in different life domains characterized in people with multiple sclerosis

In a cross-sectional survey study of people with multiple sclerosis (MS) conducted in Sweden, approximately half of 4,052 participants said that tiredness/fatigue was their most limiting symptom.
Around a third of participants reported no life restrictions in terms of leisure activities (31.1%), work (35.7%), family (38.7%), and contact with friends/acquaintances (40.3%), while the remaining two-thirds said they experienced moderate-to-severe restrictions.
Even people with low disability levels – indicated by an Expanded Disability Status Scale (EDSS) score of 0 – reported life restrictions, with the proportion affected ranging from 39.6% for contact with friends/acquaintances to 45.7% for leisure activities. Predictors of restrictions in work and life domains included MS type, sociodemographic factors, type of most limiting symptom, and EDSS score.