Relationship between blood pressure variability and brain volumes in post-menopausal women


  • Greater systolic blood pressure variability (SBPV) was associated with significant reductions in hippocampal volume and increases in white and gray matter lesions, but without cognitive decline in elderly post-menopausal women without a history of cardiovascular disease (CVD) and with few modifiable CV risk factors.

Why this matters

  • The results of this study suggest a potential role of SBPV as a prognostic indicator even in the absence of documented CV risk factors and that monitoring this variable over time could be a useful strategy for preserving cognitive health in elderly post-menopausal women.