Parkinson’s disease and deficits in temporally predictive mechanisms


  • Parkinson’s disease (PD) patients demonstrated a deficit in reaction time to temporally predictable cues but not unpredictable cues, and this effect was driven by faster reaction times among control patients to predictable cues which was not observed in PD patients.

Why this matters

  • This study suggests PD patients have diminished capacity to extract temporal information from predictable stimuli, and the effect is common to both movement and speech, indicating a relationship between PD pathology and sensorimotor deficits in temporal predictive mechanisms.