New advances in digital screening tools for Alzheimer’s disease

  • Several computerized cognitive tests have been developed to detect cognitive decline in people with Alzheimer’s disease (AD). This study compared telephone-Montreal Cognitive Assessment (T-MoCA) and Telephone Interview for Cognitive Status (TICS) as screening tests for preclinical AD.
  • Findings from this study demonstrated that both tests were able to effectively detect cognitive impairment (receiver operating characteristic area under the curve: TICS=0.889; T-MoCA=0.902), and negatively correlated with AD biomarker (tau/amyloid beta 1-42; TICS: r= -0.372; P=0.001; T-MoCA: r=-0.480; P<0.001).
  • According to the authors, T-MoCA and TICS may provide additional support for identifying cognitive impairment via remote administration for preclinical AD, particularly in older adults.