New advances in digital screening tools for Alzheimer’s disease

Several computerized cognitive tests have been developed to detect cognitive decline in people with Alzheimer’s disease (AD). This study compared telephone-Montreal Cognitive Assessment (T-MoCA) and Telephone Interview for Cognitive Status (TICS) as screening tests for preclinical AD.
Findings from this study demonstrated that both tests were able to effectively detect cognitive impairment (receiver operating characteristic area under the curve: TICS=0.889; T-MoCA=0.902), and negatively correlated with AD biomarker (tau/amyloid beta 1-42; TICS: r= -0.372; P=0.001; T-MoCA: r=-0.480; P<0.001).
According to the authors, T-MoCA and TICS may provide additional support for identifying cognitive impairment via remote administration for preclinical AD, particularly in older adults.