Long-term efficacy of focused ultrasound unilateral subthalamotomy for Parkinson’s Disease

Unilateral Magnetic Resonance-guided Focused Ultrasound subthalamotomy (FUS-STN) has a wide range of benefits and can effectively improve several symptoms associated with Parkinson disease (PD). This association was tested in 32 patients with PD after receiving 36 months of treatment.
Researchers found an improvement of Movement Disorders Society-Unified Rating scale (MDS-UPDRS) motor part (III) score by 52.3% from baseline (before treatment) to 3 years (P<0.001), for the treated hemibody off-medication. At 3 years, the total MDS-UPDRS III off-medication score was 22.9% lower than at baseline (P<0.001). No adverse events were noted.
The treatment of PD motor symptoms with FUS-STN proved effective for long-term benefit in patients and supports the role in the clinical management of movement disorders.