Summary Summary Short summary of a recent publication, written by scientific experts. Published: 07 Mar 2019

Impaired insulin sensitivity, metabolic status, and worsening cognition in HIV-infected patients

Takeaway

  • Hyperinsulinemia and impaired insulin sensitivity are associated with cognitive decline in antiretroviral therapy (ART)- treated HIV-infected patients.

Why this matters

  • Identification of hyperinsulinemia and abnormalities in lipid and cholesterol metabolism in worsening cognition in HIV-infected patients may lead to effective interventions that restore brain insulin sensitivity.