Impact of conditioned pain modulation on trigeminal nociception in people with migraine headaches


  • Conditioned pain modulation (CPM) of the nociceptive blink reflex (nBR) is reduced in people with migraine, suggestive of impaired inhibition of trigeminal nociception.

Why this matters ?

  • A deficiency in inhibition of trigeminal nociception may be linked to development of migraines and a risk factor for headaches.