High variability between different diagnostic criteria for refractory myasthenia gravis


  • Using the International Consensus Guidance (ICG) and REGAIN diagnostic criteria resulted in the diagnosis of significantly fewer people with refractory myasthenia gravis (MG), with worse disease severity.

Why this matters

    This study highlights the conceptual differences in the word ‘refractory’ and emphasizes the need for unified criteria so that comparison studies are more valid and meaningful.