High-dose erythropoietin in preterm infants with intraventricular hemorrhage: a randomized trial

Takeaway

  • Preliminary results from a randomized controlled trial report no significant effect on brain injury scores post high-dose erythropoietin in preterm infants with intraventricular hemorrhage (IVH).

Why this matters?

  • There is observational data on preterm infants with IVH treated with erythropoietin gaining long-term neurodevelopmental benefits. The Erythropoietin for the Repair of Cerebral Injury in Very Preterm Infants (EpoRepair) trial is a randomized trial investigating the short-term efficacy of this intervention. 

  • The long-term effect of erythropoietin on neurological development remains to be seen.