Hemorrhagic markers in cerebral amyloid angiopathy-related intracerebral hemorrhage


  • Cortical superficial siderosis (cSS), a key hemorrhagic marker of cerebral amyloid angiopathy (CAA)-related intracerebral hemorrhage (ICH), is increased in the ICH-affected hemisphere compared to the non-affected hemisphere; no difference was observed for amyloid burden.

Why this matters

    These findings provide new insights into the underlying mechanisms of brain hemorrhage in CAA and may facilitate the identification of therapies targeted toward lowering ICH risk in these individuals.