Examining the efficacy of autologous tumor lysate-loaded dendritic cell vaccination in patients with glioblastoma

Takeaway

  • Including autologous tumor lysate-loaded dendritic cell vaccination (DCVax-L) to standard of care (SOC) in patients with newly diagnosed glioblastoma (nGBM) and recurrent glioblastoma (rGBM) can provide a significant extension to overall survival (OS).

Why this matters?

  • Glioblastoma is an aggressive type of brain cancer that is associated with poor clinical outcomes.  

  • New treatments that can extend OS are needed for patients with nGBM and rGBM.