Effect of vitamin D levels on multiple sclerosis outcomes


  • There is no association between genetically predicted 25-hydroxyvitamin D (25[OH]D) levels and disease outcomes in people with multiple sclerosis (MS).

Why this matters?

  • Low levels of 25(OH)D may be associated with increased disease activity in people with MS.

  • Levels of 25(OH)D may be partially genetically determined via polygenic scores (PGS) and may be useful in determining disease outcomes in people with MS.