Takeaway
There is no association between genetically predicted 25-hydroxyvitamin D (25[OH]D) levels and disease outcomes in people with multiple sclerosis (MS).
Why this matters?
Low levels of 25(OH)D may be associated with increased disease activity in people with MS.
Levels of 25(OH)D may be partially genetically determined via polygenic scores (PGS) and may be useful in determining disease outcomes in people with MS.