Early anatomical signatures as potential biomarkers in paediatric patients with Friedreich’s ataxia


  • Cross-sectional multimodal MRI-based study identifies neuroanatomical abnormalities in specific regions of the spinal cord and brain of paediatric Friedreich’s ataxia (FRDA) patients.

Why this matters

  • Early detection of structural damage in peripheral and central nervous system could be useful in developing prognostic tools and designing therapeutic trials in patients with FRDA.