Do obesity and race explain differential neurocognitive outcomes in individuals from the US?


  • Individuals with obesity have lower baseline cognition, but decline more slowly after accounting for systolic blood pressure (SBP) and fasting plasma glucose (FPG), although race does not modify the association.

Why this matters

  • The relationship between obesity and cognitive impairment is important given the global increases in obesity prevalence.

  • Elucidating the relationships between obesity and cognition, in addition to whether race modulates any interactions, may provide clinicians with insight as to how to intervene to address both cognitive impairment and obesity.