Correlation between imaging modalities and Parkinson’s disease severity


  • Both dopaminergic positron emission tomography (PET) and diffusion magnetic resonance imaging (MRI) are sensitive to the neural degeneration, motor symptoms, and cognitive impairments characteristic of Parkinson’s disease (PD).

Why this matters ?

  • The low strength of correlation between PET and diffusion MRI imaging indicates that the two assessments measure unique mechanisms of nigrostriatal degeneration in PD and may be useful for monitoring different facets of PD progression.