Coexistence of amyloid and tau can lead to decreased connectivity in Alzheimer’s disease


  • Coexistence of amyloid and tau deposition can decrease structural connectivity in patients with Alzheimer’s disease (AD); whereas, tau deposition alone induces compensatory responses against early neuronal injury and chronic inflammation associated with normal aging.

Why this matters

  • Amyloid may play a crucial role in alternating structural connectivity in AD.