Summary Summary Short summary of a recent publication, written by scientific experts. Published: 27 Nov 2018

Coexistence of amyloid and tau can lead to decreased connectivity in Alzheimer’s disease

Takeaway

  • Coexistence of amyloid and tau deposition can decrease structural connectivity in patients with Alzheimer’s disease (AD); whereas, tau deposition alone induces compensatory responses against early neuronal injury and chronic inflammation associated with normal aging.

Why this matters

  • Amyloid may play a crucial role in alternating structural connectivity in AD.