Clarifying the relationship between sphenopalatine ganglion volume and cluster headache

  • Mean sphenopalatine ganglion (SPG) volume was found to be significantly larger in individuals with cluster headache compared to healthy controls (P<0.001).
  • SPG volume was also found to be significantly larger on the side of the brain associated with pain in individuals with cluster headache (P<0.001).
  • The authors concluded that SPG is a reliable marker for cluster headache and may be associated with symptomatology, although further studies are needed.