Brain scans reveal low levels of amyloid-β plaques in people with narcolepsy

Takeaway

  • Brain amyloid-β deposition has been quantified in people with narcolepsy type 1 (NT1) who may have a reduced risk for Alzheimer’s disease.

Why this matters 

    NT1 is an orphan chronic disease caused by reduced orexin neurons, and allows for an interesting model to understand the relationship between amyloid-β and orexin pathways.