Takeaway
Both the globus pallidus internus (GPi) and the subthalamic nucleus (STN) are effective targets for deep brain stimulation in isolated dystonia but GPi may be better for those with axial symptoms while STN showed a larger clinical response within 1 month and lower battery consumption.
Why this matters
Direct comparison of GPi and STN may identify parameters where one technique is superior to the other and identify optimal targets in isolated dystonia.