Takeaway
Migraine, particularly migraine with aura (MA) is associated with increased levels of clotting factors, potentially explaining the link between migraine and stroke/cardiovascular disease (CVD).
Why this matters
Migraine is associated with increased risk of stroke and CVD; however, the mechanisms underlying this association are not well understood.
A better understanding of these mechanisms could lead to discovery of therapeutic targets in migraine and/or prevention of migraine-related stroke.