Summary Summary Short summary of a recent publication, written by scientific experts. Published: 27 Nov 2018

Amyloid-β accumulation, white matter abnormalities and hypometabolism in Alzheimer’s disease

Takeaway

  • In patients with Alzheimer’s disease (AD), interaction between amyloid-β deposition and disruption of white matter integrity drives limbic glucose hypometabolism.

Why this matters

  • Better understanding of the link between pathological processes of amyloid-β deposition and disruption of white matter integrity could help guide treatment of AD.