A novel individual biomarker: sleep EEG envelope spectrum


  • Sleep EEG envelope spectrum, which reflects periodic fluctuations in EEG amplitude, is associated with neuronal firing. It can potentially function as a biomarker for an individual, as it can reasonably predict sex and demonstrate changes with age.

Why this matters?

  • The sleep EEG signal has demonstrated reliable intra-individual stability, and inter-individual variability. It is linked to a number of clinical conditions. Data on the sleep EEG envelope – the instantaneous amplitude of oscillations after filtering for certain frequencies – is lacking.

  • Sleep EEG envelope spectrum can be a potential marker of individual variations, e.g. demographic data, pathological conditions, or psychological traits.