A Canadian matched cohort study of cancer incidence in multiple sclerosis


  • The incidence of breast and colorectal cancers are no different in people with and without multiple sclerosis (MS). However, bladder cancer incidence was more frequent in people with MS.

Why this matters

  • Assessing whether the number of cancer cases is excessive in clinical trials evaluating disease-modifying treatments of MS (i.e. pharmacovigilance) is only possible if there is an appropriate comparison with MS-specific cancer incidence rates.